Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Medium or Average
Based on 14 Reviews
6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
L-Theanine
200 mg
*
Inositol
100 mg
*
Top Medical Research Studies
9
ITPP enhances heart attack recovery
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Read More
Most Useful Reviews
9
Normalised pulse
This is an excellent calming aid and has notably reduced my high heart rate. I take it nightly with bacopa, and I've been sleeping better, waking up less frequently. My pulse is now normal. I appreciate this product.
Read More
9
Reduced heart rate
12 people found this helpful
After my mother passed away, I sought something calming, settling on L-theanine. It provided me with a sense of peace and balance. Unlike sleeping pills, it worked for me. Notably, my pulse, which was typically high, dropped significantly. After just two days of taking it, my pulse reduced from 90–105 to 75–85. I urge anyone facing similar issues to give it a try.
Read More
0
Increased heart rate
3 people found this helpful
Unfortunately, I did not tolerate this product well. Even at half the dosage, I experienced rapid heartbeats and heightened anxiety. Despite trying the 100 mg version, the effects were the same.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
ITPP enhances heart attack recovery
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 14 Reviews
6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Normalised pulse
This is an excellent calming aid and has notably reduced my high heart rate. I take it nightly with bacopa, and I've been sleeping better, waking up less frequently. My pulse is now normal. I appreciate this product.
Read More
9
Reduced heart rate
12 people found this helpful
After my mother passed away, I sought something calming, settling on L-theanine. It provided me with a sense of peace and balance. Unlike sleeping pills, it worked for me. Notably, my pulse, which was typically high, dropped significantly. After just two days of taking it, my pulse reduced from 90–105 to 75–85. I urge anyone facing similar issues to give it a try.
Read More
0
Increased heart rate
3 people found this helpful
Unfortunately, I did not tolerate this product well. Even at half the dosage, I experienced rapid heartbeats and heightened anxiety. Despite trying the 100 mg version, the effects were the same.
Read More
0
Severe migraines
3 people found this helpful
I didn’t notice an effect, but I gave it to a loved one with hypertension and headaches. After one capsule, he had a severe headache, migraines, and panic attacks, leading us to call an ambulance. He described the experience as if he were withdrawing from heroin, and it took another two days to feel better. He's now quit smoking.
Read More
9
Eased anxiety symptoms
1 people found this helpful
L-theanine has genuinely helped me manage my anxiety. Whenever I felt anger boiling up and my heart racing, I noticed that since starting this, those feelings have subsided. Now, I can get through my day without feeling overly stressed. A very effective product for me.
Read More
Frequently Asked Questions
9
Reduced heart rate
12 people found this helpful
After my mother passed away, I sought something calming, settling on L-theanine. It provided me with a sense of peace and balance. Unlike sleeping pills, it worked for me. Notably, my pulse, which was typically high, dropped significantly. After just two days of taking it, my pulse reduced from 90–105 to 75–85. I urge anyone facing similar issues to give it a try.
0
Heart attack fears
1 people found this helpful
After purchasing L-theanine, I experienced severe ectopic heartbeats and rapid heart rate after following the recommended dosage for a week. It was frightening, and I nearly sought medical attention until I identified the cause. I found many others reported similar reactions and believe there should be a warning about this. I won't use it again.
0
Negative side effects
1 people found this helpful
I was enthusiastic about L-theanine for anxiety and mood but faced severe side effects such as trembling, heart palpitations, and difficulty concentrating. Eventually, I tried it at night, but I felt no positive effects. It simply didn’t work for me.
9
Normalised pulse
This is an excellent calming aid and has notably reduced my high heart rate. I take it nightly with bacopa, and I've been sleeping better, waking up less frequently. My pulse is now normal. I appreciate this product.
9
Eased anxiety symptoms
1 people found this helpful
L-theanine has genuinely helped me manage my anxiety. Whenever I felt anger boiling up and my heart racing, I noticed that since starting this, those feelings have subsided. Now, I can get through my day without feeling overly stressed. A very effective product for me.
0
Severe migraines
3 people found this helpful
I didn’t notice an effect, but I gave it to a loved one with hypertension and headaches. After one capsule, he had a severe headache, migraines, and panic attacks, leading us to call an ambulance. He described the experience as if he were withdrawing from heroin, and it took another two days to feel better. He's now quit smoking.
8.5
Reduced anxiety levels
I tried L-theanine for my anxiety disorder, taking it alongside propranolol. After a month, I discontinued propranolol, and I found that about 85% of my anxiety vanished. I still occasionally experience palpitations, but now I sleep soundly without nightmares.
6
Calming effect
I feel calmer after taking this, especially when irritable or anxious. It helps to eat it alongside coffee.
0
Panic attacks
I didn't like it; I had panic attacks with coffee. Before that, I took Nutricost, which was good.
0
Increased heart rate
3 people found this helpful
Unfortunately, I did not tolerate this product well. Even at half the dosage, I experienced rapid heartbeats and heightened anxiety. Despite trying the 100 mg version, the effects were the same.
9
ITPP enhances heart attack recovery
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
References
- Oknińska M, El-Hafny-Rahbi B, Paterek A, Mackiewicz U, Crola-Da Silva C, et al. Treatment of hypoxia-dependent cardiovascular diseases by myo-inositol trispyrophosphate (ITPP)-enhancement of oxygen delivery by red blood cells. J Cell Mol Med. 2020;24:2272. doi:10.1111/jcmm.14909
